PFOA has Become Very Controversial
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Perfluooctanoic Acid (PFOA) a synthetic chemical used in the manufacture of nonstick coatings has become controversial because in animal studies, exposure to PFOA lead to:

• Serious changes in organs including the brain, prostate, liver, thymus, and kidneys. All of which showed toxicity.

• Death of several rat pups due to PFOA exposure.

• Changes in the pituitary glands in female rats, at all doses. The pituitary controls growth, reproduction, and many metabolic functions. Changes in the size of the pituitary indicate toxicity.

PFOA has been associated with tumors in at least four different organs in animal tests, and has been implicated in an increase in prostate cancer in PFOA plant workers.

The various PFOA doses used in these animal experiments weren't necessarily the same exposure levels you might get from nonstick cookware. But they clearly show the potential danger from PFOA.